软组织再生的局部和全身疗法:叙述性审查
Caroline J Cushman1, Andrew F Ibrahim1, Alexander D Smith1
1School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
The Yale journal of biology and medicine
|October 1, 2024
概括
类疗法在关节疼痛和软组织再生方面表现有前途. 口服和关节内剂的使用都具有益处,但为了广泛的临床使用,需要进一步的研究.
科学领域:
- 生物医学科学 生物医学科学
- 药理学 药理学是指药理学的学科.
- 再生医学是一种再生医学.
背景情况:
- 肌肉骨关节疼痛源于诸如关节炎和软组织损伤等疾病.
- 类疗法提供了一种安全的,最少侵入性的方法来治疗关节疼痛和炎症.
- 这种疗法旨在为关节疾病提供治疗效益.
研究的目的:
- 审查关于用于软组织再生的口服和关节内类药物的文献.
- 在人体试验中评估药物输送的注射途径 (RoA).
- 评估在治疗关节疼痛和促进愈合方面的潜力.
主要方法:
- 使用PubMed进行了全面的文献搜索.
- 使用医疗主题标题 (MeSH) 用于疗法,软组织再生和RoA.
- 包括关于机制,临床结果和评论的文章,但不包括不足或证据不足的研究.
主要成果:
- 确定了在软组织修复方面有效的多种.
- 口服提供全身效益,而关节内提供局部效果的再生.
- 这两种管理途径都面临生物可用性和吸收方面的挑战.
结论:
- 类治疗正在成为软组织再生手术的有希望的替代方案.
- 关节内和口腔在促进组织修复方面表现出明显的优势.
- 进一步的研究是必要的,以充分理解和利用新兴的疗法.
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