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Updated: Jul 2, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
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在子眼部生物流体中使用敏感和选择性的LC-MS/MS方法对加蒂夫洛克萨和德克萨的药理动力学分析

Arpon Biswas1,2, Abhijit Deb Choudhury1,2, Anjali Mishra1

  • 1Pharmaceutics and Pharmacokinetic Division, CSIR-Central Drug Research Institute, Lucknow, India.

Journal of mass spectrometry : JMS
|October 1, 2024
PubMed
概括

一种新的生物分析方法准确地量化了眼中的加蒂夫洛克萨 (GAT) 和甲 (DEX). 这种经过验证的LC-MS/MS技术支持对细菌角膜炎治疗的药理学研究.

关键词:
在 LCMS/MS 中使用.抗生素抗生素是一种抗生素.这是一种皮质类固醇.眼睛滴滴滴滴滴滴滴滴滴滴滴滴滴滴滴眼液是一种催液.

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Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...