双臂间的缩血压差异与左心室的集中度和集中重塑有关
Annelise M G Paiva1,2, Maria I C M Gomes1, Alana C M Gomes1
1Centro de Pesquisas Clínicas do Centro Universitário Cesmac, Maceió, AL.
Journal of hypertension
|October 1, 2024
概括
显著的手臂间静脉血压差异 (IASD) >15 mmHg,特别是当使用同时 (IASDsim2) 或顺序 (IASDseq3) 协议测量时,与不良的左心室 (LV) 重塑有关,包括LV集中度和集中重塑.
科学领域:
- 心脏病学 心脏病学
- 心血管生理学心血管生理学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 较高的手臂间静脉血压差异 (IASD) >15 mmHg与心血管风险增加有关.
- 连接IASD与心血管结果的确切机制仍然不完全理解.
- 左心室 (LV) 改造是心血管健康和疾病进展的关键指标.
研究的目的:
- 通过各种测量方案评估的IASD>15 mmHg与不良的左心室 (LV) 重塑之间的关联.
- 确定特定的IASD测量方法是否与LV改造的特定模式相关.
- 探索不同IASD评估协议在确定心血管风险方面的临床实用性.
主要方法:
- 一项涉及605名接受临床和心声学评估的个体的横截面研究.
- 获得了三对同时手臂血压 (BP) 读数.
- 使用七个不同的协议计算IASD,包括同时和连续的BP测量标准.
主要成果:
- 通过同时测量最后两个BP对 (IASDsim2) 和特定的顺序右-左-右臂序列 (IASDseq3) 定义的IASD>15mmHg与LV集中度和LV集中重塑有关.
- 对于LV的集中度的赔率比为3.24 (IASDsim2) 和2.56 (IASDseq3).
- 对于LV同心重塑的几率比率为4.12 (IASDsim2) 和4.16 (IASDseq3).
- 没有发现IASD>15 mmHg (根据任何标准) 与 LV 缩之间存在关联.
结论:
- 特定的IASD测量协议 (IASDsim2和IASDseq3) 与不利的LV重塑有显著的关联,特别是LV集中度和集中重塑.
- 这些发现凸显了IASDsim2和IASDseq3在评估异常IASD和相关心血管风险方面的潜在临床实用性.
- 进一步的研究可能会完善这些特定的IASD标准在临床实践中用于风险分层的使用.
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