饮食在非传染性疾病发展中的作用:聚焦肠道微生物群
Andrea Fričová1, Anna Zavaďáková1, Monika Bludovská1,2
1Department of Public Health and Preventive Medicine, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Central European journal of public health
|October 1, 2024
概括
饮食显著影响肠道微生物群的多样性,影响肥胖等非传染性疾病. 健康的饮食习惯对于预防肠道失调和相关健康问题至关重要.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 预防医学 预防医学
背景情况:
- 饮食成分迅速且显著地影响肠道微生物群的多样性.
- 肠道微生物群的改变与非传染性疾病 (NCD) 的发展有关.
- 西方饮食越来越受欢迎,并与负面的健康结果有关.
研究的目的:
- 审查不同的饮食如何影响肠道微生物组合.
- 探索饮食改变在预防或减缓非传染性疾病发展中的作用.
- 了解饮食,肠道微生物群和非传染性疾病之间的联系.
主要方法:
- 系统的PubMed文献综述和手工搜索的参考文献.
- 包括2000年至2024年以英语出版的研究.
- 分析饮食对肠道微生物群和非传染性疾病的影响.
主要成果:
- 饮食通过对肠道微生物群及其代谢物的影响,显著影响NCD的发展.
- 西方饮食促进肠道失调,导致通过细菌产物如脂多糖 (LPS) 和三甲基胺N氧化物 (TMAO) 导致慢性炎症.
- 失生症和相关的炎症有助于肥胖,2型糖尿病和心血管疾病的发病.
结论:
- 健康的饮食习惯对于预防肠道失生症至关重要.
- 饮食干预可以帮助管理肥胖和其他非传染性疾病的流行率和发病率的上升.
- 通过饮食保持平衡的肠道微生物群是整体健康和疾病预防的关键.
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