相关实验视频

Updated: Jun 11, 2025

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

51.9K

依赖IL-7和依赖IL-7R的人类T细胞的IL-7依赖和独立系

Carlos A Arango-Franco1,2,3, Masato Ogishi4, Susanne Unger5,6

  • 1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.

The Journal of clinical investigation
|October 1, 2024
PubMed
概括

遗传IL-7缺乏症导致结合性免疫缺陷 (CID) 与严重的T细胞淋巴缺陷,与IL-7R缺乏症不同. 这表明T细胞发育的替代途径,可能涉及甲状腺 stromal lymphopoietin.

关键词:
细胞因子 (cytokines) 是一种细胞因子.遗传性疾病是一种遗传性疾病.遗传学 是一个遗传学.免疫学 免疫学 免疫学在T细胞发育过程中,

更多相关视频

A Strategy for the Study of IL-9-Producing Lymphoid Cells in the Nippostrongylus brasiliensis Infection Model08:38

A Strategy for the Study of IL-9-Producing Lymphoid Cells in the Nippostrongylus brasiliensis Infection Model

Published on: March 3, 2023

1.3K
Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells14:23

Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells

Published on: April 16, 2012

24.0K

相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
959
Lineage Commitment01:21

Lineage Commitment

Commitment is the  process whereby stem cells:
3.0K
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
680