相关实验视频

Updated: Jun 11, 2025

Visualization and Quantification of Endogenous Intra-Organelle Protein Interactions at ER-Mitochondria Contact Sites by Proximity Ligation Assays
08:27

Visualization and Quantification of Endogenous Intra-Organelle Protein Interactions at ER-Mitochondria Contact Sites by Proximity Ligation Assays

Published on: October 20, 2023

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Sec23IP招募VPS13B/COH1到ER退出站点-Golgi接口,用于管状ERGIC形成

Yuanjiao Du1, Xinyu Fan1, Chunyu Song2

  • 1Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.

The Journal of cell biology
|October 1, 2024
PubMed
概括

研究人员发现,Sec23交互蛋白 (Sec23IP) 作为VPS13B适配器,将其招募到ER退出站点,以促进运输. 这种相互作用对于预防科恩综合征,一种发育障碍至关重要.

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Targeting proteins to the ER
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