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Updated: Jun 11, 2025

Quantification of Subcellular Glycogen Distribution in Skeletal Muscle Fibers using Transmission Electron Microscopy
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Quantification of Subcellular Glycogen Distribution in Skeletal Muscle Fibers using Transmission Electron Microscopy

Published on: February 7, 2022

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低碳水化合物可用性运动对肌肉糖原和细胞信号的反应:系统性审查和元分析

Javier Diaz-Lara1,2, Gorka Prieto-Bellver3, Amelia Guadalupe-Grau4,5

  • 1Performance and Sport Rehabilitation Laboratory, Faculty of Sport Sciences, University of Castilla-La Mancha, 45071, Toledo, Spain. javier.diazlara@uclm.es.

Sports medicine (Auckland, N.Z.)
|October 1, 2024
PubMed
概括

与运动一起的碳水化合物限制会增加特定的代谢基因mRNA (PDK4,UCP3,GLUT4),但不会增加线粒体基因 (PGC-1α,TFAM). 显著的糖原耗尽增强了这些效应,并增强了PGC-1α mRNA.

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Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique07:20

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Metabolic States of the Body: Fasting and Starvation

During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
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Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
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