急性COVID-19症状概况与长期COVID流行之间的关联:基于人口的跨部门研究
Jana L Hirschtick1,2, Elizabeth Slocum1, Yanmei Xie1
1Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, United States.
JMIR public health and surveillance
|October 1, 2024
概括
急性COVID-19症状概况显著预测长期COVID风险. 多症状和呼吸短促群体显示长期COVID流行率最高,突出了针对性查的必要性.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 严重的急性COVID-19与长期COVID (COVID-19后的情况) 风险增加有关.
- 有限的研究存在于急性症状概况及其与长期COVID发病的关联.
- 了解这些关联对于风险分层和患者护理至关重要.
研究的目的:
- 调查急性COVID-19症状集群与长期COVID的患病率之间的关系.
- 为了确定与患长期COVID的更高风险相关的特定症状概况.
- 为临床实践和未来研究方向提供信息.
主要方法:
- 对已确认感染SARS-CoV-2的成年人进行了基于人口的调查.
- 潜在类分析确定了不同的急性COVID-19症状集群.
- 多项物流和修改的波桑回归分析检查了预测因素和长期COVID关联.
主要成果:
- 确定了6个急性COVID-19症状集群,最常见的是类似流感的症状和发烧.
- 长期COVID的患病率在多症状 (39.7%) 和呼吸短促 (22.4%) 群体中最高.
- 多症状集群显示了长期COVID的最高调整流行率 (aPR 6.1).
结论:
- 急性COVID-19症状概况是长期COVID风险的重要指标.
- 在评估长期COVID风险时,临床医生应考虑症状集群.
- 建议根据急性症状对高风险患者进行主动查.
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