基于网络的Pleasure&Pregnancy计划用于治疗无法解释的不孕症:一个随机对照试验
F Dreischor1, E A F Dancet2, C B Lambalk3
1Department of Obstetrics and Gynaecology, Centre for Reproductive Medicine, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Human reproduction (Oxford, England)
|October 1, 2024
概括
快乐与怀孕 (P&P) 计划并没有改善无法解释的不孕症夫妇的自然怀孕率. 虽然电子健康干预并没有增加受孕率,但它显示了改善女性性健康和性满意度的潜力.
科学领域:
- 生殖医学 生殖医学
- 不孕症治疗 不孕症治疗
- 性健康干预措施 性健康干预措施
背景情况:
- 以前的研究表明,性健康干预措施可以提高怀孕率.
- 电子健康计划在不孕症性健康方面的有效性仍未通过大型试验进行评估.
研究的目的:
- 为了确定Pleasure&Pregnancy (P&P) 计划是否能提高自然怀孕的持续怀孕率,而不是对伴侣有不明原因的不孕症的预期管理.
主要方法:
- 一个全国性的,多中心,无盲随机控制的优越性试验,涉及700对有不明原因不育的夫妇.
- 参与者被随机分配1:1到基于网络的P&P计划或预期的管理.
- 主要结果是6个月内自然怀孕持续怀孕,次要结果包括怀孕时间和性健康.
主要成果:
- 在P&P组 (19.4%) 和预期管理 (22.6%) 之间,持续怀孕率没有显著差异.
- 观察到高消耗率 (57%) 和有限的参与 P&P 计划.
- 虽然怀孕率没有受到影响,但P&P计划显示女性性快乐,高潮和满意度有所改善.
结论:
- 不建议使用P&P程序来增加未解释不育的自然怀孕率.
- 该计划可以被视为增强性健康的工具.
- 低参与度凸显了对生育电子卫生干预措施的用户体验研究的需要.
相关概念视频
Infertility in Females
288
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
288
In Vitro Fertilization
229
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
229
Infertility in Males
253
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
253


