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Updated: Jun 11, 2025

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays
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德乌克拉维西提尼布对TYK2的多作用全抑制:来自计算模拟的见解

Yiqiong Bao1, Ran Xu2, Jingjing Guo3

  • 1Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.

Computational biology and chemistry
|October 1, 2024
PubMed
概括

德乌克拉维西替尼 (DEU) 通过稳定其JH2和JH1域之间的抑制接口来全质抑制TYK2. 这种机制增强了负调节,为TYK2针对自身免疫性疾病的治疗提供了洞察力.

关键词:
所有的法规都是单一的.自制抑制是自制的.杰克·杰克是什么意思激酶活动的激酶活性.伪基因酶-基因酶相互作用

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