Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Viral co-infection with SARS-CoV-2 in hospitalized Peruvian patients during 2020-2021.

Revista peruana de medicina experimental y salud publica·2026
Same author

Implementation of a SARS-CoV-2 genomic surveillance network as a strategy to face other health challenges in Peru.

Revista peruana de medicina experimental y salud publica·2026
Same author

Pathogenesis and host response to a novel Tacaribe virus isolate in experimentally-infected Jamaican fruit bats.

bioRxiv : the preprint server for biology·2026
Same author

Hanta on the Hondius - public health and bioethical perspectives of the recent <i>Andes</i> hantavirus cruise ship outbreak.

New microbes and new infections·2026
Same author

Bundibugyo Ebolavirus outbreak in the Democratic Republic of the Congo and Uganda: rapid assessment from the European Society of Clinical Microbiology and Infectious Diseases Emerging Infections Subcommittee.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same author

Avian Influenza in Humans: Virology, Transmission, and Clinical Priorities.

QJM : monthly journal of the Association of Physicians·2026

相关实验视频

Updated: Jul 10, 2026

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
10:25

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

4.6K

早期SARS-CoV-2循环的血清学证据在秘鲁利马,2020年.

Andres Moreira-Soto1,2, Maria Paquita García3, Gloria Arotinco-Garayar3

  • 1Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Virology, Berlin, Germany.

The American journal of tropical medicine and hygiene
|October 1, 2024
PubMed
概括

早期未检测到的严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 在秘鲁的循环导致了高的COVID-19死亡率. 准确的诊断确认对于了解流行病传播和改善疫情管理至关重要.

更多相关视频

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

2.8K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.1K

相关实验视频

Last Updated: Jul 10, 2026

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
10:25

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

4.6K
Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

2.8K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.1K

科学领域:

  • 病毒学 病毒学
  • 流行病学 流行病学
  • 公共卫生 公共卫生

背景情况:

  • 秘鲁在2021年初经历了最高的COVID-19人均死亡率.
  • 导致高死亡率的因素包括社会经济不平等,医疗保健系统的不准备以及监测局限性.
  • 早期,未被发现的SARS-CoV-2循环可能会显著加剧死亡率.

研究的目的:

  • 调查SARS-CoV-2在秘鲁引入和传播的时间.
  • 评估早期,未被发现的病毒传播在秘鲁高COVID-19死亡率中的作用.
  • 强调诊断确认在跟踪流行病轨迹中的重要性.

主要方法:

  • 在1441名发烧患者 (2019年8月至2021年5月) 中对SARS-CoV-2抗体进行血清检测.
  • 使用化学发光免疫测试,替代病毒中和测试,斑块减少中和测试 (PRNT) 和贪测试.
  • 使用易受,暴露,感染和恢复 (SEIR) 数学模型来估计有效的繁殖数量.

主要成果:

  • 没有早期样本 (2020年1月至3月) 被PRNT证实,与2020年4月以后的样本不同 (P <0.0001).
  • 2020年4月中旬,SARS-CoV-2抗体检测率为0.9%,这表明流通开始于2020年3月初至中旬.
  • 增加的抗体狂热度和SEIR模型结果表明,SARS-CoV-2在2020年2月底/3月底开始循环.

结论:

  • 在秘鲁,SARS-CoV-2的早期引入和传播早于官方检测,导致死亡率高.
  • 准确的诊断确认对于了解疾病传播和流行病动态至关重要.
  • 这项研究强调了早期检测和精确测试对于有效的传染病爆发管理的必要性.