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儿童和青少年的结直肠腺癌

R Bigliardi¹, M Morici², G Messere¹

¹Servicio de Gastroenterología Pediátrica, Hospital Nacional Prof. A. Posadas, Buenos Aires, Argentina.

Revista de gastroenterologia de Mexico (English)

|October 1, 2024

概括

儿童结肠直肠癌是罕见的和积极的,经常呈现含糊不清的症状,如腹痛和出血. 这项研究发现,在患有粘膜腺癌的儿科患者中,没有预易性疾病和不良预后.

科学领域:

儿科瘤学儿科瘤学
胃肠道瘤学胃肠道瘤学
癌症研究癌症研究

背景情况:

结肠直肠腺癌在儿科患者中不常见.
症状往往是非特异性的,导致诊断延迟,并且在呈现时疾病已晚期.

研究的目的:

描述儿童和青少年结直肠腺癌的临床表现和疾病进展.
确定年轻患者这种罕见癌症的潜在诱导因素.

主要方法:

2000年至2021年间诊断出结直肠腺癌的八名儿科患者的回顾性评估.
分析临床数据,组织学,分期,治疗和生存结果.
对相关易感性疾病的调查.

主要成果:

平均年龄为16岁;常见症状包括腹痛,腹部瘤,直肠出血和体重减轻.
所有病例都是粘膜腺癌,其中60%位于右结肠;没有一个有明显的倾向性疾病.
诊断时的高级阶段是常见的 (50%的IV阶段),3年总生存率为25%.

结论:

儿科结直肠癌,特别是粘膜腺癌,呈现出侵略性,预后不佳.
考虑在儿童中患有无法解释的腹痛,质量或下肠道出血的结肠直肠癌,特别是随着体重减轻.

关键词:

腺癌是什么? 腺癌是什么?青少年青少年青少年青少年青少年孩子孩子孩子孩子结肠直肠癌是一种癌症.癌症颜色直肠癌癌症孩子们的孩子们儿科瘤学儿科瘤学儿科瘤学儿科瘤学

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