通过适应性放射疗法个性化放射治疗:兴趣和挑战
Olivier Riou1, Jessica Prunaretty1, Morgan Michalet1
1Department of Radiation Oncology, Institut du cancer de Montpellier, Montpellier, France; Fédération universitaire d'oncologie radiothérapie de Méditerranée Occitanie, université de Montpellier, Montpellier, France; U1194, Inserm, Montpellier, France.
概括
在线适应性放射治疗 (ART) 通过每天适应患者解剖学,最大限度地减少副作用和改善瘤向来个性化癌症治疗. 这种先进的技术利用新技术提高了精度和结果.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 癌症治疗方法 癌症治疗方法
背景情况:
- 适应性放射治疗 (ART) 通过适应日常解剖变化,使得个性化癌症治疗成为可能.
- 历史上在线执行,ART现在提供每日在线适应,以提高精度.
研究的目的:
- 详细介绍在线ART模式的好处,优势,限制和局限性.
- 评估在线ART特别适用的临床情况.
- 讨论未来在线ART开发的挑战和解决方案.
主要方法:
- 在线适应性放射治疗过程的描述.
- 对线上ART的MR线性加速器和CBCT线性加速器的评估.
- 分析包括人工智能和多式联络成像在内的技术进步.
主要成果:
- 在线ART允许日常定制,以获得最佳的目标覆盖率和最小的利率.
- 它减少了毒性,并使瘤剂量升级成为可能.
- 图像和人工智能的技术进步对其实施至关重要.
结论:
- 在线ART,在MR和CBCT线性加速器上可用,在癌症治疗个性化方面提供了显著的优势.
- 需要进一步开发以应对挑战并扩大其临床应用.
- 这项技术有望将毒性降到最低,并改善治疗结果.
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