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Updated: Jun 11, 2025

Single Particle Cryo-Electron Microscopy: From Sample to Structure
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使用贝叶斯基因算法从电子显微镜图像中获得3D原子重建:可能性,洞察力和局限性

Tom Stoops1,2, Annick De Backer1,2, Ivan Lobato3

  • 1EMAT, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
|October 1, 2024
PubMed
概括

贝叶斯基因算法从显微镜图像中重建纳米粒子结构. 这项研究优化了算法的效率,使得更大的纳米颗粒的详细分析能够达到10纳米.

关键词:
3D特征表征 3D特征表征定量电子显微镜的使用.扫描传输电子显微镜扫描传输电子显微镜统计参数估计的估计.

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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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