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Updated: Jun 13, 2025

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps
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Published on: July 19, 2024

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人类黑色皮质素-4受体特异性正统纳米体agonist的结构阐明

Thomas Fontaine1, Andreas Busch1, Toon Laeremans1

  • 1Confo Therapeutics N.V, Ghent, Belgium.

Nature communications
|October 1, 2024
PubMed
概括

研究人员开发了高度特定的纳米体,针对黑色素皮质受体4 (MC4R) 作为潜在的抗肥胖疗法. 这些特定于MC4R的纳米体比目前的激动剂具有更高的选择性,减少了目标外效应.

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