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Updated: Jun 13, 2025

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
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Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Published on: May 24, 2017

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在核酸切除修复中,切割前复合物的分子结构和功能动态

Jina Yu1,2, Chunli Yan1,2, Tanmoy Paul1,2

  • 1Department of Chemistry, Georgia State University, Atlanta, GA, USA.

Nature communications
|October 1, 2024
PubMed
概括

这项研究揭示了核酸切除修复 (NER) 切割前复合体 (PInC) 的结构,详细说明了TFIIH,XPG和XPA如何协调DNA修复. 这为基因组完整性和相关疾病提供了洞察力.

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