狗的皮下和皮肤巨细胞瘤的组织病理特征
Stella Minnoye1, Shana De Vos2,3, Samuel Beck4
1Anicura Dierenkliniek Randstad, Frans Beirenslaan 155, Borsbeek, 2150, Belgium. stella.minnoye@anicura.be.
Acta veterinaria Scandinavica
|October 1, 2024
概括
狗的皮下巨细胞瘤 (scMCTs) 与皮肤巨细胞瘤 (cMCTs) 相比,呈现出明显的组织病理特征. 皮下MCT更频繁地被赋予高档基乌佩尔分类,表明潜在的预后差异.
科学领域:
- 兽医病理学 兽医病理学
- 狗类瘤学 狗类瘤学
- 皮肤病理学 皮肤病理学
背景情况:
- 巨细胞瘤 (MCTs) 是常见的狗皮肤瘤.
- 区分皮肤 (皮肤) 和皮下MCT对于预后至关重要.
- 现有的分级系统 (Patnaik,Kiupel) 主要是为皮肤MCT开发的.
研究的目的:
- 为了比较犬类皮下MCT (scMCT) 和皮肤MCT (cMCT) 的信号和本病理特征.
- 为了确定这两种瘤类型之间的相似之处和差异.
- 评估分级系统对scMCT和cMCT的适用性.
主要方法:
- 对2020年9月至2023年7月期间诊断的犬类MCT病例的回顾性分析.
- 数据收集包括信号,瘤位置,组织病理特征和淋巴结状况.
- 在scMCTs和cMCTs之间比较线粒细胞计数,核特征和基乌佩尔等级.
主要成果:
- 在scMCTs和cMCTs之间,品种分布有显著差异.
- 在scMCTs和cMCTs之间没有观察到线粒细胞计数的显著差异.
- 与cMCT相比,scMCT表现出更频繁的无糖体,奇怪的核和多核.
- scMCTs比cMCTs (11.9%) 更多地被赋予基乌佩尔高等级 (17.5%).
结论:
- 在狗的scMCT和cMCT之间存在细胞病理学上的差异.
- 皮下MCT使用基乌佩尔系统更频繁地被归类为高等级.
- 需要进一步的研究来将这些组织病理学发现与临床结果相关联.
更多相关视频
08:57Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
1.9K
07:32Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
Published on: April 12, 2024
1.2K
相关概念视频
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...