在手术期间肌肉运动引起的潜在变化是由于波动的下部运动神经元背景刺激性?
Martín J Segura1, María E Talarico1, Lucas Piantoni2
1Department of Clinical Neurophysiology, National Pediatric Hospital "Dr. Juan P. Garrahan", Buenos Aires, Argentina.
概括
较低运动神经元兴奋度的波动对运动唤起潜力 (MEP) 的变化比预期的要少. 皮层脊髓杆的有效性是可再生MEP在异常脊柱病患者中的关键.
科学领域:
- 神经科学是一个神经科学.
- 临床电生理学 临床电生理学
背景情况:
- 运动唤起的潜能 (MEP) 对于评估皮质脊髓管完整性至关重要.
- 欧洲议会议员的变化可能受到几个因素的影响,包括低运动神经元 (LMN) 刺激性.
- 了解MEP变化的来源对于准确的临床解释很重要.
研究的目的:
- 为了研究波动的LMN刺激性对MEP变异性的贡献.
- 为了比较MEP与H-反射 (HRs) 的变异性,在患有异常脊椎病的儿科患者中.
主要方法:
- 这项试点研究涉及六名患有异常学脊椎病的儿科患者.
- 术内H反射 (HRs) 和MEP从肌底肌肉中被唤起和记录.
- 计算了幅度和面积的变化系数 (CVs),并将高层和欧洲议员之间的变化系数进行了比较.
主要成果:
- 与HR相比,MEP在振幅 (CV 24.6 ± 3) 和面积 (CV 21.8 ± 4.8) 上表现出明显更高的变化 (振幅CV 3.5 ± 4.4;面积CV 3.4 ± 4.5).
- HR和MEP变化参数之间的相关系数较低,表明共享差异有限.
- 这些发现表明,LMN激发性波动只占MEP变化的很小一部分.
结论:
- 在LMN兴奋度的波动可能在MEP变化中扮演的角色不如以前所认为的那么重要.
- 皮质脊髓飞弹的LMN池的稳定性和招募效率对于获得可重复的欧洲议员至关重要.
- 需要进一步的研究来阐明其他导致MEP变化的因素.
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