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Updated: Jun 11, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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针对性蛋白质降解技术能否在抗老年症药物的开发中提供潜在的突破?

Baichen Xiong1, Zuoaoyun Song1, Leyan Wang2

  • 1School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.

ACS chemical neuroscience
|October 2, 2024
PubMed
概括

小分子粉样β (Aβ) 降解剂在阿尔茨海默病 (AD) 治疗方面显示出前景. 这种新兴的向蛋白质降解技术为AD提供了新的治疗途径,解决了当前治疗方法的局限性.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.氨基βββββββββββββββββββββββββ抗体是对抗体的重要组成部分.蛋白质降解 蛋白质降解小分子的小分子.

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