在非处方鼻喷雾剂中药理成分的冗余性
Lily N Trinh1, Diandra K Smith1, Edward D McCoul1,2
1Department of Otolaryngology-Head and Neck Surgery Tulane University New Orleans Louisiana USA.
OTO open
|October 2, 2024
概括
非处方药 (OTC) 鼻喷雾剂显示出大量的成分重叠,最常见的是像oxymetazoline这样的鼻腔脱凝剂. 这种市场冗余需要患者对药物标签的认识,以便明智地选择药物.
科学领域:
- 药理学 药理学是指药理学的学科.
- 制药科学 制药科学
- 消费者健康 消费者健康
背景情况:
- 非处方药 (OTC) 鼻喷雾剂广泛用于各种鼻子疾病.
- 对医疗保健提供者和患者来说,了解活性成分和市场流行率至关重要.
- 之前对OTC鼻喷雾配方的分析是有限的.
研究的目的:
- 评估和确定非处方药 (OTC) 鼻喷雾剂中成分的流行率.
- 在OTC鼻喷雾市场中确定常见的活性成分和配方模式.
主要方法:
- 通过在2023年8月在五家全国零售药房清单OTC鼻喷雾剂,进行了一项横截面研究.
- 关于活性成分的数据从商业网站和知名的医疗信息数据库 (MedlinePlus,drugs.com) 中收集.
- 对于已识别的活性成分和产品配方,计算了频率统计.
主要成果:
- 在五家药房中发现了12个不同的品牌和49种独特的产品.
- 鼻腔除凝剂,特别是氧美zoline (51 种产品) 和phenylephrine,是最常见的,其次是化 (40 种产品).
- 鼻内类固醇 (流动,三氨,布德森,莫梅) 和抗胰岛素药物 (阿泽拉斯,克罗莫林) 的品牌配方较少.
结论:
- 在OTC鼻喷雾市场,配方和活性成分的多余性显著.
- 医疗保健提供者应该意识到这种市场和,以指导患者选择合适的OTC鼻喷雾剂.
- 鼓励患者仔细阅读产品标签对于做出关于OTC鼻喷雾使用的明智决策至关重要.
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