补充阿基尼因在亚临床死肠炎挑战期间对 brojlers 的肠道微生物平衡的影响
Shahna Fathima1, Walid G Al Hakeem1, Revathi Shanmugasundaram2
1Department of Poultry Science, University of Georgia, Athens, GA, United States.
Frontiers in physiology
|October 2, 2024
概括
补充氨酸的饮食有助于恢复患有死肠炎 (NE) 的 brojlers的肠道微生物平衡. 虽然125%和135%的氨酸水平改善了微生物组成,但它们并没有显著改变短链脂肪酸概况.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 微生物学 微生物学
- 动物营养 动物营养
背景情况:
- 结核性肠炎 (NE) 是家禽的一种重大肠道疾病,其特征是肠道失调.
- 氨酸在肠道健康和免疫功能中起着至关重要的作用.
- 了解阿基尼因在NE期间对肠道微生物群的影响对于家禽生产至关重要.
研究的目的:
- 在亚临床NE条件下调查高氨酸饮食 (125%和135%) 对肠道微生物多样性和组成在 brojlers的影响.
- 评估阿金宁补充剂减轻NE诱导的肠道失调症的潜力.
主要方法:
- 一项为期28天的实验,涉及120只一天大的肉小,分为四个治疗组:未感染 + 基底,NE + 基底,NE + 125% 氨酸和NE + 135% 氨酸.
- 使用*Eimeria maxima*卵囊和*Clostridium perfringens*接种诱导NE.
- 肠道微生物组成使用安普利康测序来分析.
- 测量了Cecal短链脂肪酸 (SCFA) 的度.
主要成果:
- NE挑战显著减少了微生物多样性,并改变了关键细菌系 (Firmicutes, Bacteroidota) 和物种的丰富性.
- 125%和135%的氨基酸饮食都部分或完全恢复了特定细菌群的丰富性,包括*Bacteroidota*, *Odoribacteraceae*, *Oscillospiraceae*, *Odoribacter*, *O. splanchnicus*和 *M. cottocaccae*.
- 虽然氨酸饮食改善了微生物组成,但它们没有显著地恢复28日的Cecal Propionate,Butyrate或总SCFA度.
结论:
- 补充氨酸 (125%和135%) 可以有效地恢复肠道微生物的组成在肉经历亚临床死肠炎挑战.
- 在NE期间维护肠道微生物平衡中,氨酸在维持肠道微生物平衡中的作用很重要.
- 结合阿金和其他料添加剂的进一步研究可能对面对NE的家禽的综合性肠道健康管理有益.
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