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鉴定和验证高性心肌病中与自相关的基因

Rong-Bin Qiu1,2, Shi-Tao Zhao1,2, Zhi-Wei Li3

  • 1Department of Cardiovascular Surgery, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

Experimental and therapeutic medicine
|October 2, 2024
PubMed
概括

与自相关的基因 (ARG) 在缩性心肌病 (HCM) 中表现异常. 这些基因,包括EIF4EBP1和MCL1,可以作为HCM的诊断生物标志物和治疗点.

关键词:
自自是自的过程.生物信息学分析分析生物标志物 生物标志物我们的数据库数据库数据库数据库.过度缩性心肌病变性心脏病.

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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