基于心力衰竭的生物阻抗测试的可穿戴设备:临床相关性:系统审查
Luis Giménez-Miranda1,2,3, Santiago F Scagliusi4,5, Pablo Pérez-García4,5
1Internal Medicine Department, Virgen del Rocío University Hospital, 41013 Seville, Spain.
Reviews in cardiovascular medicine
|October 2, 2024
概括
可穿戴生物阻抗装置显示出监测心力衰竭液体过载和预测恶化的事件的前景. 需要进一步的研究来优化它们对预后的临床影响.
科学领域:
- 生物医学工程 生物医学工程
- 心脏病学 心脏病学
- 医疗器械 医疗器械
背景情况:
- 心力衰竭 (HF) 是住院的主要原因,通常是由液体过载引起的.
- 组织水分的生物阻抗 (BI) 监测为管理HF拥堵提供了潜力.
- 可穿戴的BI设备正在成为远程高频患者监控的工具.
研究的目的:
- 系统地审查可穿戴生物阻抗设备的临床相关性,用于监测心力衰竭患者的液体状况.
- 评估这些设备的诊断和预后能力.
主要方法:
- 按照PRISMA的指导方针,对五个主要数据库 (PubMed,Scopus,Cochrane,Web of Science,Embase) 进行了系统的文献审查.
- 包括的研究评估了HF患者的可穿戴BI设备,并使用ROBINS工具评估了偏差风险.
- 数据提取的重点是设备在流体监测中的有效性,HF事件的预测和预后价值.
主要成果:
- 审查了涉及535名参与者的10篇文章.
- 在HF患者和对照人群之间,以及在充血性和非充血性HF患者之间,观察到BI值的显著差异.
- 设备的灵敏度为70.0%,特异性为89.1%,用于预测HF恶化的事件.
- 降低R80kHz与增加全因死亡率 (HR 5.51) 和高频率入院 (HR 4.96) 相关.
结论:
- 可穿戴的BI设备在检测流体过载方面是有效的,并显示出HF管理的潜力.
- 与标准护理相比,需要进一步的技术进步和临床研究来确定它们的常规使用,并优化预后影响.
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