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Updated: Jun 11, 2025

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通过SNAIL抑制ECM重塑导致血管疾病遗传风险的LRP1抑制

Lu Liu1, Joséphine Henry1, Yingwei Liu1

  • 1Université Paris Cité, Inserm, PARCC, Paris, France.

Circulation research
|October 2, 2024
PubMed
概括

在LRP1的遗传变异影响血管疾病的风险. SNAIL抑制LRP1的表达,影响光滑肌肉细胞功能和细胞外矩阵重塑,这可能解释其在多种血管疾病中的作用.

关键词:
诱导多能干细胞的诱导干细胞.低密度脂蛋白受体相关的蛋白-1-1肌细胞,光滑肌肉的肌肉.血管疾病是血管疾病.

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