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Updated: Jun 11, 2025

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使用电喷射电离和离子移动性光谱法-质谱法对抗癌药物原体的表征

Pallab Basuri1, Marc Safferthal2, Borislav Kovacevic3

  • 1Institute of Chemistry, Humboldt-Universität zu Berlin, 12489 Berlin, Germany.

Journal of the American Society for Mass Spectrometry
|October 2, 2024
PubMed
概括

研究人员使用离子运动质谱法检测出抗癌药物palbociclib,copanlisib和olaparib. 这些药物在离子化过程中形成异构体,称为原构体,由于多个质子化位点,影响了它们的化学分析.

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