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Updated: Jun 11, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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从热力学模型预测p53依赖的细胞转换

Pankaj Gautam1, Isabella Ciuta2, Vladimir B Teif2

  • 1Theoretical and Computational Biophysical Chemistry Group, Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab 140001, India.

The Journal of chemical physics
|October 2, 2024
PubMed
概括

这项研究模拟了p53信号网络和3D基因组组织如何影响恶性细胞命运过渡. 热力学模型显示,与基因促进体结合的p53可以起到相变的作用,影响癌细胞状态.

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