环境空气污染和中国因精神分裂症住院的情况
Lijun Bai1,2,3,4, Yunxing Jiang1,2,3,4, Kai Wang1,2,3,4
1Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
JAMA network open
|October 2, 2024
概括
空气污染的短期增加,特别是细颗粒物 (PM2.5) 和二氧化,会增加精神分裂症发作风险. 持续多天的污染增加进一步增加了这种风险,这表明需要在精神分裂症预防中控制污染.
科学领域:
- 环境健康 环境健康
- 精神病学流行病学 精神病学流行病学
- 公共卫生 公共卫生
背景情况:
- 精神分裂症的发作可以由短期的环境因素引发.
- 很少有研究研究了短期空气污染增加与精神分裂症风险之间的联系.
研究的目的:
- 为了确定短期空气污染增加是否与精神分裂症发作有关,独立于绝对水平.
- 为了评估持续的空气污染是否在多天内增加,扩大精神分裂症的风险.
主要方法:
- 一个全国性的,基于人口的,时间分层的病例交叉研究,使用中国住院记录 (2013-2017).
- 分析了PM2.5,PM10,二氧化,二氧化硫,臭氧和一氧化碳的每日度.
- 使用条件后勤回归来评估空气污染指标 (绝对值,每日增加,持续增加) 与精神分裂症住院患者之间的关联.
主要成果:
- 对PM2.5,PM10,二氧化,二氧化硫和一氧化碳的六天移动平均空气污染增加 (lag0-5) 与更高的精神分裂症住院率有关.
- 对于每个污染物的四分位数间范围增加,观察到特定的风险百分比增加.
- 持续增长的空气污染持续时间 (长达4天以上) 与更大的精神分裂症住院风险有关.
结论:
- 环境空气污染的短期增加与精神分裂症发作风险增加有关.
- 未来的精神分裂症预防策略应该考虑空气污染的增加,特别是持续的事件,以及绝对度.
- 这项研究强调了监测和减轻空气污染对心理健康的重要性.
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