在三级保健中心的慢性肝病患者中的肝细胞癌:描述性的横截面研究
Arun Gnawali1, Rahul Pathak1, Dinesh Koirala1
1Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal.
JNMA; journal of the Nepal Medical Association
|October 2, 2024
概括
肝细胞癌 (HCC) 影响3.75%的慢性肝病患者. 与酒精有关的肝硬化是最常见的原因,大多数患者在晚期呈现症状.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 肝细胞癌 (HCC) 是主要的主流肝脏恶性瘤.
- 常见的病因包括病毒性肝炎,酒和自身免疫性肝炎.
- 患者经常出现晚期疾病,排除治愈干预措施.
研究的目的:
- 为了确定诊断为慢性肝病的患者肝细胞癌 (HCC) 的患病率.
- 在这个队列中确定与HCC相关的风险因素和出现症状.
主要方法:
- 在一个单一的三级保健中心进行了一项描述性,横截面的研究.
- 数据是从2020年3月至2022年8月期间的住院患者收集的.
- 使用了总人口抽样和以95%置信区间的点患病率估计.
主要成果:
- 在1440名患有慢性肝病的患者中,HCC的患病率为3.75% (95% CI: 2.77-4.73).
- 在54名患者中诊断出肝细胞癌 (HCC),其中88.89%呈现症状.
- 体重减轻是最常见的症状 (64.81%);酒精消费 (68.52%) 和吸烟 (74.07%) 是普遍存在的.
结论:
- 肝细胞癌 (HCC) 是慢性肝病患者的重大公共卫生问题.
- 与酒精有关的肝硬化成为本研究人群中主要的潜在疾病.
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