患病率,原因和因子与故意不遵守处方药物相关:一个基于人口的研究
Tatiana da Silva Sempé1, Emilia da Silva Pons2, Tatiane da Silva Dal Pizzol1,2
1Universidade Federal do Rio Grande do Sul, School of Pharmacy, Graduate Program in Pharmaceutical Assistance - Porto Alegre (RS), Brazil.
概括
许多患者故意不坚持药物治疗,经常由于副作用而减少药物剂量. 识别不坚持因素是改善治疗坚持策略的关键.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 蓄意不遵守药物治疗是管理慢性疾病的一个重大挑战.
- 了解患者对药物坚持的行为对于有效的治疗结果至关重要.
研究的目的:
- 为了确定故意不遵守药物治疗的患病率.
- 确定导致故意不遵守的主要原因和相关因素.
主要方法:
- 一项基于人口的横截面研究利用了国家药物获取,使用和推广合理使用调查 (PNAUM) 的数据.
- 一个全面的调查问卷收集了有关社会人口统计,慢性疾病,药物使用,自我评估健康和与药物相关的行为信息.
- 调整为变异的Poisson回归模型被用于数据分析.
主要成果:
- 这项研究包括31573名参与者;8.8%的参与者有意增加药物剂量,21.2%的参与者有意减少药物剂量.
- 副作用是减少剂量最常见的原因,而剂量增加没有特定的原因.
- 年轻人,人均收入较低的人,以及报告自己健康状况较差的参与者更有可能改变药物剂量.
结论:
- 很大一部分人表现出故意不遵守处方药疗法.
- 解决患者的需求和观点对于制定有针对性的策略至关重要,以提高药物坚持和提高治疗疗效.
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