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在阿姆斯特丹共识之后,死产中的胎盘病变:系统性审查和元分析

Brenda F Narice¹, Victoria Byrne², Mariam Labib²

¹Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Tree Root Walk, Sheffield, S10 2SF, UK; Sheffield Teaching Hospitals NHS Foundation Trust, Tree Root Walk, Sheffield, S10 2SF, UK.

|October 2, 2024

概括

胎盘疾病是死胎的主要原因之一. 孕产妇和胎儿的血管阻塞是与死胎相关的常见胎盘病变,但只有孕产妇的阻塞在术后仍然显著.

科学领域:

产科和妇科产科和妇科
围产儿医学围产儿医学
病理学病理学病理学

背景情况:

胎盘疾病是全球死产的主要原因.
标准化的胎盘组织学命名对于临床实用性和研究至关重要.
阿姆斯特丹共识分类方便国际对胎盘发现进行比较.

研究的目的:

系统地审查和分析全球最常见的与死胎相关的胎盘病变.
用标准化分类来识别与死产有显著关联的胎盘病变.
调查妊娠年龄对胎盘病变与死产之间的关联的影响.

主要方法:

发表的研究的系统审查和元分析.
包括18项研究,包括3082个胎盘.
基于阿姆斯特丹共识对胎盘组织学分类的分析.

主要成果:

孕产妇血管缺血和胎儿血管缺血是死产中最常见的胎盘病变.
这些病变在死胎中比活胎更频繁 (分别为OR 3.0和OR 5.12).
经过对妊娠年龄进行调整后,只有母亲的血管缺血仍然是预产期死产的重要预测因素.

结论:

孕产妇和胎儿血管缺血是与死胎相关的关键胎盘病变.
需要进一步研究胎盘病变的病理生理学.
更好的理解可能会导致更好的风险评估和干预措施,以减少死产.

关键词:

"阿姆斯特丹标准"就是阿姆斯特丹标准.进行元分析分析.胎盘胎盘胎盘胎盘一个死胎,一个死胎.系统性审查系统性审查

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