静脉鼻支架后,内压力和静脉鼻压力之间的相关性发生变化
Ankitha M Iyer1, Jackson P Midtlien2, Carol Kittel3
1Neurological Surgery and Radiology, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA.
Journal of neurointerventional surgery
|October 2, 2024
概括
异常性内高血压 (IIH) 管理可能会受到先前静脉鼻支架 (VSS) 的影响. 与没有VSS患者相比,患有VSS患者的脑脊液 (CSF) 压力相对于静脉压力更高.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 血管医学 血管医学
背景情况:
- 异常性内高血压 (IIH) 和脑静脉外流障碍 (CVD) 的病理生理学仍然不完全理解.
- 已知静脉鼻压力和开口压力 (OP) 之间的相关性,但先前有静脉鼻支架 (VSS) 的患者的数据有限.
研究的目的:
- 研究心血管疾病患者的静脉鼻压力和OP之间的关系.
- 确定以前的VSS是否会改变这种关系.
主要方法:
- 对心血管疾病患者进行诊断性脑静脉扫描,其次是腰椎穿刺的脑静脉扫描的回顾性图表审查.
- 从2016年到2024年对206名患者进行的216项手术的分析.
主要成果:
- 在所有患者中,观察到OP和状/上部状鼻 (SSS) 压力之间存在中度,几乎为一比一的相关性.
- 患有先前VSS的患者 (n=32) 呈现出改变的关系:相对于静脉压力,相比于没有支架的患者,OP更高.
- 在OP固定在21mmHg和BMI固定在30kg/m2的情况下,预测的平均SSS压力在有支架的患者 (16.91mmHg) 和没有支架的患者 (19.47mmHg) 中较低.
结论:
- 在心血管疾病患者中,OP和静脉鼻压力之间存在着强烈的关系.
- 之前的VSS显著改变了OP-静脉压力关系,导致相对较高的CSF压力.
- 这些发现表明,对管理IIH患者有VSS史的潜在临床影响.
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