Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Neuron Structure01:30

Neuron Structure

12.7K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
12.7K
Neural Circuits01:25

Neural Circuits

1.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multimodal evidence for a mechanistic model of working memory deficits in schizophrenia.

medRxiv : the preprint server for health sciences·2026
Same author

Map of spiking activity underlying change detection in the mouse visual system.

Cell·2026
Same author

Quantitative anatomy and biophysical modeling of ascending neuromodulatory systems in the developing rat neocortex.

PLoS computational biology·2026
Same author

Resonance-driven enhancement of sleep spindles using thalamic temporal interference stimulation.

bioRxiv : the preprint server for biology·2026
Same author

Linking reduced prefrontal microcircuit inhibition in schizophrenia to EEG biomarkers in silico.

PLoS computational biology·2026
Same author

Deep-learning-assisted simulation of a cortical circuit: integrating anatomy, physiology and function.

bioRxiv : the preprint server for biology·2026

相关实验视频

Updated: Jun 11, 2025

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

1.7K

大规模机械模型的大脑电路与生物物理和形态详细的神经元.

Salvador Dura-Bernal1,2, Beatriz Herrera3, Carmen Lupascu4

  • 1State University of New York (SUNY) Downstate Health Sciences University, Brooklyn, New York 11203 salvador.dura-bernal@downstate.edu.

The Journal of neuroscience : the official journal of the Society for Neuroscience
|October 2, 2024
PubMed
概括

大规模的机械脑模型整合复杂的数据,揭示神经机制和疾病生物标志物. 这些多尺度模型有助于我们更好地了解大脑功能,并有助于开发新的治疗方法.

关键词:
生物物理详细模型.大脑的电路循环.机械模型是机械模型.建模 建模模型 建模模型形态详细的神经元的神经元.多分区神经元模型网络模型 网络模型模拟器模拟器模拟器模拟器

更多相关视频

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

8.5K
Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents
17:37

Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents

Published on: March 4, 2012

34.7K

相关实验视频

Last Updated: Jun 11, 2025

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

1.7K
Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

8.5K
Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents
17:37

Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents

Published on: March 4, 2012

34.7K

科学领域:

  • 计算神经科学是一种神经科学.
  • 系统神经科学 系统神经科学
  • 神经科学建模神经科学建模

背景情况:

  • 神经科学研究越来越多地以数据为导向,大脑电路的大量数据集.
  • 整合和解释这些复杂的数据集带来了重大挑战.
  • 超级计算的进步使复杂的,大规模的生物物理脑模型成为可能.

研究的目的:

  • 审查大脑电路的大规模机械模型的最新进展.
  • 突出实验数据的整合到详细的生物物理模型.
  • 展示这些模型在理解大脑功能和疾病中的应用.

主要方法:

  • 开发大型,机械,多尺度生物物理电路模型.
  • 整合各种实验数据 (电路组成,连接性,活动).
  • 在多个尺度 (如LFP,EEG/MEG) 上模拟和分析神经活动.

主要成果:

  • 展示了各种大脑区域 (海马体,皮质,丘脑) 综合模型的示例.
  • 模型准确地预测了实验记录背后的细胞和电路机制.
  • 对神经和精神疾病 (,抑郁症,精神分裂症,帕金森病) 的模拟生物标志物.

结论:

  • 机械多尺度模型对于整合实验数据和推进大脑研究至关重要.
  • 这些模型为神经编码,行为,疾病机制和治疗干预提供了洞察力.
  • 模拟者,实验家和临床医生之间的跨学科合作对于未来的进步至关重要.