体感神经假体的临床应用和未来翻译
Emily Graczyk1,2, Brianna Hutchison3, Giacomo Valle4,5
1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 emily.graczyk@case.edu.
概括
体感神经假体通过电刺激恢复感官反. 最近的临床研究表明,它们有潜力改善感官障碍患者的感知,功能和心理健康.
科学领域:
- 生物医学工程 生物医学工程
- 神经科学是一个神经科学.
- 康复技术 康复技术 康复技术
背景情况:
- 体感神经假体的目的是恢复触觉和自身感知反.
- 这些系统将传感器数据与神经系统的电刺激相结合.
- 进步正在将重点从技术开发转移到临床应用.
研究的目的:
- 在人类临床试验中审查当前的神经刺激方法.
- 总结关于体感神经假体影响的临床发现.
- 讨论未来面临的广泛翻译挑战.
主要方法:
- 审查现有文献和正在进行的临床研究.
- 对传感反的神经刺激技术的分析.
- 感知,功能和心理结果的综合.
主要成果:
- 临床研究正在加速,证明了翻译潜力.
- 体感神经假体影响知觉,功能和心理状态.
- 目前正在开发先进的刺激模式,以实现自然反.
结论:
- 体感神经假体对有感官丧失的人来说非常有前途.
- 需要进一步的研究来克服临床翻译的挑战.
- 优化刺激是增强感官信息传递的关键.
相关概念视频
Somatosensation
36.5K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.5K
Overview of Somatic Sensory Pathways
4.3K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.3K
Sensory Perception: Organization of the Somatosensory System
2.9K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
2.9K


