视频囊肠镜中的计算机辅助小体形态测量量:一种新开发的软件可以量化小肠缩
Nicoletta Nandi1, Matilde Topa1, Alessandro Rimondi2
1Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
概括
一个新的软件工具分析了小肠囊内镜 (SBCE) 图像,以量化乳病 (CeD) 患者的状缩. 这种方法显示出对非侵入性评估肠道损伤的前景.
科学领域:
- 胃肠病学 胃肠病学
- 医疗成像医学成像
- 计算病理学计算病理学
背景情况:
- 小肠囊内镜 (SBCE) 用于非响应性腹腔疾病 (CeD).
- 需要一种量化,非侵入性的方法来评估小肠缩.
研究的目的:
- 开发和验证一种新的软件工具,用于使用SBCE量化状缩.
- 评估该工具在将缩性粘膜与非缩性粘膜区分的准确性.
主要方法:
- 分析了CeD患者 (2018-2020) 的SBCE框架.
- 感兴趣的区域被选择并使用NIH图像处理软件进行处理.
- 一个3D表面图表宏观量化了肠道小密度.
主要成果:
- 该软件以77%的灵敏度和79%的特异性区分了缩性和非缩性粘膜.
- 在缩和非缩框架之间观察到中位密度得分的显著差异 (p < 0.001).
- 曲线下的面积 (AUC) 是0.805.5.
结论:
- 开发的SBCE软件有效量化了状缩.
- 需要在外部队列中进一步验证以确认适用性.
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