Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

313
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
313

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Case Report: Dramatic metabolic improvement with tirzepatide in a patient with acquired partial lipodystrophy following hematopoietic stem cell transplantation.

Frontiers in endocrinology·2026
Same author

Thalidomide for CGD-related inflammatory bowel disease: A randomized, double-blind trial.

Journal of human immunity·2026
Same author

A Novel NPHS1-Associated Phenotype Characterized by Recurrent Transient Proteinuria.

Case reports in nephrology·2026
Same author

Extracellular FKBP12 Inhibits Tacrolimus Translocation to Peripheral Blood Mononuclear Cells Reducing Immunosuppressive Effects: An In Vitro Study.

Therapeutic drug monitoring·2026
Same author

Successful Treatment of CNS-PTLD Using Systemic and Intrathecal Rituximab and Donor Lymphocyte Infusion.

Pediatrics international : official journal of the Japan Pediatric Society·2026
Same author

Clinical characteristics and anti-ZSCAN1 antibody titer analysis in a nationwide survey of ROHHAD (-NET) syndrome.

The Journal of clinical endocrinology and metabolism·2026

相关实验视频

Updated: Jun 11, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
07:39

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

Published on: June 6, 2025

37

[儿科急性髓性白血病] 这种疾病是什么?

Hiroshi Moritake1

  • 1Division of Pediatrics, Department of Developmental and Urological Reproductive Medicine, Faculty of Medicine, University of Miyazaki.

[Rinsho ketsueki] The Japanese journal of clinical hematology
|October 2, 2024
PubMed
概括

日本的儿科急性髓性白血病 (AML) 有不同的亚型. 虽然一些AML类型是可以治愈的,但复发的病例,特别是新的AML,需要新的治疗策略.

科学领域:

  • 血液学 血液学 血液学
  • 儿科瘤学 儿科瘤学
  • 临床研究 临床研究

背景情况:

  • 急性髓性白血病 (AML) 占日本儿童白血病诊断的约25%,每年约有150例新病例.
  • 儿科AML被分为与唐氏综合征相关的骨髓性白血病 (ML-DS),急性肌细胞性白血病 (APL) 和 de novo AML.
  • 结果在亚型之间有很大差异,ML-DS具有很高的存活率,APL是可治愈的,而de novoAML在缓解和复发方面存在挑战.

研究的目的:

  • 审查日本三种主要儿科AML亚型的治疗方法.
  • 为了从日本进行的过去临床研究中提供背景.
  • 突出对复发性或耐火性新型AML的有希望的新型治疗方案.

主要方法:

  • 关于日本儿童AML的过去临床研究的文献综述.
  • 对ML-DS,APL和de novoAML治疗结果的分析.
  • 识别和讨论复发/耐药新型AML的新兴疗法.

主要成果:

  • 患有ML-DS的患者表现出超过80%的无事件生存率,尽管复发病例的预后不佳.
  • 使用全转网红酸和三氧化,APL是高度可治愈的.
  • De novo AML显示,最初的缓解失败率为10%,缓解后复发率为30%左右.
关键词:
急性促细胞性白血病是什么在新的急性髓性白血病中.唐氏综合征是什么意思 唐氏综合征儿科急性骨髓性白血病患者的情况

更多相关视频

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

18.1K
Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
09:57

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Published on: March 5, 2018

29.2K

相关实验视频

Last Updated: Jun 11, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
07:39

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

Published on: June 6, 2025

37
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

18.1K
Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
09:57

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Published on: March 5, 2018

29.2K

结论:

  • 目前的治疗策略为不同小儿AML亚型提供了不同的结果.
  • 复发和耐药的新型AML仍然是一个重大的临床挑战.
  • 新的治疗途径对于改善难以治疗的儿科AML群体的治疗结果至关重要.