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基于NitraTh表位素的新抗原疫苗用于有效的瘤免疫疗法

Wanli Zhang1, Xupeiyao Shi1, Shitong Huang1

  • 1Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 211198, People's Republic of China.

Cancer immunology, immunotherapy : CII
|October 2, 2024
PubMed
概括

这项研究引入了一种新的新抗原疫苗策略,使用"NitraTh表位"来绕过CD4+T细胞预测挑战. 这些疫苗有效地抑制瘤生长,并通过调节巨细胞来重新编程瘤微环境.

关键词:
癌症免疫疗法癌症免疫疗法巨细胞是一个巨细胞.化T细胞表皮图.前列腺腺素E2是什么瘤新抗原是一种新型抗原.

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