来自治疗瘤样本的免疫细胞死亡特征预测了转移性黑色素瘤中免疫检查点治疗反应

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Huancheng Zeng1, Qiongzhi Jiang2, Rendong Zhang1

  • 1Department of Breast Surgery, Cancer Hospital of Shantou University Medical College, No. 7 Raoping Road, Shantou, 515041, Guangdong, China.

Scientific reports
|October 2, 2024
PubMed
概括

这项研究确定了9个关键的免疫细胞死亡 (ICD) 基因特征,这些特征预测了在转移性黑色素瘤中对免疫检查点阻塞 (ICB) 治疗的反应. 高的ICD分数与更好的治疗反应和更长的无进展生存率相关,有助于个性化治疗决策.

关键词:
免疫检查点封锁疗法免疫原性细胞死亡在治疗瘤样本,转移性黑色素瘤.预后 预后 预测 预测

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