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Updated: Jun 11, 2025

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Jag1 缺乏症通过T 细胞和肝细胞分化缺陷改变肝纤维化

Jan Mašek1,2,3, Iva Filipovic4, Noémi Van Hul5

  • 1Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Solna, Stockholm, Sweden. jan.masek@natur.cuni.cz.

EMBO molecular medicine
|October 2, 2024
PubMed
概括

阿拉吉尔综合征涉及由于JAGGED1突变引起的肝纤维化. 这项研究表明,Jag1缺乏的小鼠具有改变的免疫细胞和减少的肝纤维化,这些发现反映在人类患者身上.

关键词:
阿拉吉尔综合征是什么意思纤维化 纤维化 纤维化在Jagged1中,Jagged1的位置是1.没有口,没有口.这就是Treg Treg.

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