在Populus trichocarpa中的LBD转录因子的全基因组识别和基因表达网络
Hui Dang1,2, Changhong Yu1, Siyuan Nan1
1College of Forestry, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
BMC genomics
|October 2, 2024
概括
这项研究在树中确定了55个侧面器官边界域 (LBD) 转录因子,透露了它们在复杂基因网络中的植物生长和耐压力方面的作用. 这些发现增强了对发育中的LBD基因功能的理解.
科学领域:
- 植物分子生物学 植物分子生物学
- 基因组学就是基因组学.
- 植物生理学 植物生理学
背景情况:
- 侧面器官边界域 (LBD) 蛋白质是植物特有的转录因子,对发育和应激反应至关重要.
- 了解像Populus trichocarpa这样的经济重要树种中的LBD基因家族对于农业和林业应用至关重要.
研究的目的:
- 为了识别和描述Populus trichocarpa中的LBD基因家族.
- 研究PtLBD基因的进化关系,基因结构和调控元素.
- 阐明 PtLBDs 在树生长,发育和应激耐受性中的作用.
主要方法:
- 遗传学分析将PtLBD TFs分类为子家族和组.
- 基因结构分析以了解拼接模式的变化.
- 在促进区域中识别转录因子结合点和 cis 元素.
- 基因组对线性分析以比较植物物种中的PtLBD基因.
- 基因本体学 (GO) 丰富和表达模式分析.
- 多层层次的层次基因网络 (ML-hGRN) 构建.
主要成果:
- 55个PtLBDTF被确定并分为两个子家族和七个组.
- 发现了与激素信号传递和应激反应相关的基因结构变异和cis元素.
- 基因组分析显示,与尤迪科特比单一植物更强烈的对线性.
- 除其他外,PtLBD7和PtLBD20与生长和发展有关.
- ML-hGRNs揭示了PtLBDs通过复杂的网络调节的生长和承受压力.
结论:
- 树中的PtLBD基因家族多样化,在植物生长和应激适应中起着重要作用.
- 基因重复事件和监管因素有助于PtLBD的功能多样化.
- PtLBDs调解复杂的基因网络,对发展和应激弹性至关重要.
相关概念视频
General Transcription Factors
5.2K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
5.2K
Transcription Factors
75.7K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
75.7K
Cell Specific Gene Expression
4.6K
4.6K
Master Transcription Regulators
6.9K
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
6.9K


