诱导 ipsilateral 运动在健康人体双臂肌肌肉中唤起的潜能
Nijia Hu1, Meghan Tanel1, Stuart N Baker2
1NeuroMuscular Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
The European journal of neuroscience
|October 3, 2024
概括
本研究介绍了一种标准化方法,用于测量在动态讲道曲任务期间使用跨磁刺激 (TMS) 的ipsilateral运动唤起潜力 (iMEPs). 这些发现证明了一种可靠和有效的方法来评估健康成年人的视网脊柱管刺激性.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 人体生理学 人体生理学
背景情况:
- 视网脊椎管 (RST) 刺激性对于自愿运动至关重要.
- 高强度的跨磁性刺激 (TMS) 用于引起ipsilateral motor-evoked potentials (iMEPs),以评估RST功能.
- 在人类中缺乏标准化和验证的iMEP诱导方法.
研究的目的:
- 提出和验证一种标准化的方法,用于在双臂肌肌中引起和分析iMEPs.
- 评估拟议的iMEP测量协议的可靠性和有效性.
- 调查使用iMEPs来评估动态运动任务期间RST兴奋性的可行性.
主要方法:
- 24名健康的成年人执行了一个动态传教士卷曲任务,一次重复的最大负载约为15%.
- 电肌图 (EMG) 记录了来自 biceps brachii 的对侧MEP (cMEP) 和iMEP.
- 应用TMS来确定M-max,TMS热点,并在特定的肘部曲角度 (110°) 引发iMEPs.
- 将iMEP振幅正常化为cMEP振幅 (ICAR),并比较了两种分析方法 (固定时间窗口与手动发病检测).
主要成果:
- 在88%的受试者 (ICAR = 0.31 ± 0.19) 中,在背景EMG以上观察到明显的IMEP.
- 在两种分析方法之间发现了对iMEP振幅和延迟的良好至优秀的一致性 (ICC = 0.795-1.000) 和低偏差.
- 该协议在轻载动态练习中成功引发了iMEPs,证明了可行性.
结论:
- 提出并验证了一种标准化的方法,用于在动态任务期间在双臂肌中引起和分析iMEPs.
- 拟议的方法提供了可靠和有效的RST刺激性的测量.
- 该协议可用于人类研究,以调查影响RST的运动控制和神经疾病.
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