认知能力的10年变化与随后的死亡率之间的关系:来自独立和有生命力的老年人高级认知训练 (ACTIVE) 试验的发现
Diefei Chen1,2, Alden L Gross1,2, Jeanine M Parisi3
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
American journal of epidemiology
|October 3, 2024
概括
认知能力的发展轨迹,而不是训练,影响着老年人死亡率. 较高的基线认知,较慢的衰退和更好的再测试效应预测了更长的生存期,记忆训练有利于受过高等教育的人.
科学领域:
- 老年学是一门学科.
- 认知神经科学 认知神经科学
- 流行病学 流行病学
背景情况:
- 认知能力和认知能力下降与老年人死亡率有关.
- 认知干预可以提高表现和减缓衰退,但它们对死亡率的长期影响尚不清楚.
研究的目的:
- 检查认知轨迹 (截断,斜率,重新测试效应) 与老年人死亡率之间的关联.
- 评估"独立活力老年人高级认知培训" (ACTIVE) 干预措施对死亡风险的影响.
主要方法:
- 利用了来自ACTIVE试验的20年随访数据 (N=2,802).
- 采用共享的生长生存模型来分析认知轨迹和死亡率.
- 评估认知训练 (记忆,推理,处理速度) 对所有原因死亡率的影响.
主要成果:
- 较高的基线认知表现,较慢的认知衰退和更大的重新测试效应与降低死亡风险有关.
- 这些关联适用于一般和特定领域的认知能力.
- 没有观察到ACTIVE认知训练对所有原因死亡率的显著影响.
结论:
- 认知训练干预措施没有显著改变老年人的认知轨迹或死亡率.
- 高等教育水平可能会调解记忆训练的生存益处,这表明需要个性化方法.
更多相关视频
10:13Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
13.7K
06:23The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
32.2K
相关概念视频
Cognitive Development During Adulthood
65
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
65
Actuarial Approach
63
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
63
Longitudinal Research
11.9K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.9K
