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Updated: Jun 11, 2025

A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia
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A20通过调节NF-κB和JNK信号传递来对人体T细胞生存和功能产生内在影响

Gina Dabbah-Krancher1,2, Allison Ruchinskas1,2, Melissa A Kallarakal1

  • 1Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, C-2013 Bethesda, MD 20814, USA.

European journal of immunology
|October 3, 2024
PubMed
概括

通过控制NF-κB和JNK信号通路,A20蛋白对维持T细胞平衡至关重要. 它的缺失导致持续的信号传递和改变T细胞死亡敏感度.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.细胞免疫学 细胞免疫学细胞因子 (cytokines) 是一种细胞因子.信号传导传导是指信号的传导.在T细胞,T细胞.

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