静脉注射的特兰克萨姆酸用于控制在全身麻醉下外部乳囊静止术期间的出血:一项随机临床试验
Mohammad Sharifi1, Mohammad Yaser Kiarudi1, Samaneh Gholamhoseinpour-Omran2
1Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Journal of ophthalmic & vision research
|October 3, 2024
概括
静脉注射的特兰胺酸显著减少了在达克里奥西斯托里诺斯托米 (DCR) 手术期间的出血和手术时间. 这项研究表明,特兰克萨姆酸有效控制DCR手术中的手术内出血.
科学领域:
- 眼科医生 眼科 眼科
- 手术创新 在外科创新.
- 药理学 药理学是指药理学的学科.
背景情况:
- 鼻液管阻塞 (NLDO) 需要进行乳囊鼻 (DCR) 手术.
- 术内出血可能会使DCR程序复杂化,可能会增加手术时间和风险.
研究的目的:
- 评估静脉注射的松胺酸在减少外围乳囊静脉切除术 (DCR) 期间手术内出血的疗效.
主要方法:
- 一个双盲,随机的安慰剂受控试验,涉及70名接受NLDODCR的患者.
- 患者在手术前30分钟内接受了静脉注射的三胺酸 (10mg/kg) 或安慰剂.
- 在各组之间比较了手术内出血量和手术持续时间.
主要成果:
- 特兰胺酸组的手术时间显著减少 (26.03分 vs 37.74分,P < 0.001).
- 与对照组相比,干预组 (70.66毫升) 的出血量明显较低 (47.74毫升,P < 0.001).
结论:
- 术前静脉注射的特兰胺酸有效控制了DCR手术期间的手术内出血.
- 特兰胺酸为改善DCR手术结果提供了有价值的辅助.
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