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在外科手术期间管理中的肠道微生物群和益生菌:叙述性审查
Madhuri Kurdi1, Sukhminder J S Bajwa2, Ridhima Sharma3
1Department of Anaesthesiology, Karnataka Medical College and Research Institute, Hubballi, IND.
Cureus
|October 3, 2024
概括
通过益生菌和益生菌改变肠道微生物组可能会影响手术前的焦虑和术后的结果. 这种肠-大脑轴连接在外科手术前期提供了潜在的临床应用.
科学领域:
- 微生物学 微生物学
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
背景情况:
- 人的肠道是各种微生物的宿主,形成了一个复杂的生态系统.
- 新出现的证据表明,肠道微生物组与大脑 (肠-大脑轴) 之间存在联系.
- 肠道微生物组可以通过益生菌,益生菌和共生菌进行调节.
研究的目的:
- 探索在外科手术前期调节肠道微生物群的临床实用性.
- 审查肠道微生物组改变对外科手术期间焦虑和认知功能的影响.
主要方法:
- 在多个数据库 (MEDLINE,Embase,Scopus,PubMed,Google Scholar) 中进行了文献搜索.
- 包括研究动物和人类肠道微生物组变化的临床前和临床研究.
- 专注于围绕手术的因素,如焦虑溶解,益生菌/益生菌,阿片类药物,麻醉剂和压力.
主要成果:
- 肠道微生物组的改变与手术前焦虑的变化有关.
- 手术后妄想,认知功能障碍和疼痛受到肠道微生物组调节的显著影响.
- 研究表明,焦虑溶解,益生菌/益生菌,阿片类药物,麻醉剂和术后压力对肠道微生物群的影响.
结论:
- 调节肠道微生物组为外科手术前期提供了潜在的治疗策略.
- 需要对肠-大脑轴,信号通路和临床应用进行进一步的高质量研究.
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