质腺瘤:尿道狭窄的冷部分上的陷
Alexander M Oberc1, Christopher Sherman1,2, Michelle R Downes1,2
1Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Canada.
International journal of surgical pathology
|October 3, 2024
概括
质腺瘤是一种良性病变,在尿道狭窄手术期间,在冷部分经常被误诊. 第二种意见对于准确的诊断和避免不必要的恶性瘤治疗至关重要.
科学领域:
- 尿路病理学 尿路病理学
- 手术病理学手术病理学
背景情况:
- 尿道狭窄是尿路阻塞的常见原因,需要手术切除.
- 对于尿道狭窄切除的冷切口是罕见的,并且在诊断上具有挑战性.
- 像质腺瘤这样的良性病变可以在冷部分模仿恶性病变.
研究的目的:
- 评估尿道狭窄切除术中质腺瘤和其他病变的发生率.
- 在这些情况下,评估冷截面诊断的准确性.
- 突出诊断陷和专家咨询的重要性.
主要方法:
- 从2012-2022年对258次尿道狭窄切除的回顾性审查.
- 对形,癌瘤和原腺瘤的最终病理学报告的分析.
- 与最终诊断的冷截面报告进行比较,并对原性腺瘤病例进行额外审查.
主要成果:
- 在3.8%的切除中发现了质腺瘤.
- 在一个病例中,分别发现了肌肉发育不良症和状细胞癌.
- 在3.4%的病例中要求进行冷切割;在专家审查后,最初怀疑恶性瘤的两例病例被重新归类为质腺瘤.
结论:
- 由于形态变化,原性腺瘤在冷部位上存在诊断挑战.
- 病理学家可能缺乏熟悉的良性实体在罕见的冷部分设置.
- 泌尿生殖系统病理学家的第二意见对于预防恶性瘤的错误诊断是有价值的.
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