在最少侵入性食道切除 (PEPMEN) 中的甲脊椎对抗皮度止痛:一个随机控制的多中心试验
Minke L Feenstra1,2, Cezanne D Kooij3, Wietse J Eshuis1
1Department of Surgery, Amsterdam UMC Location University of Amsterdam, AGEM, Cancer Center Amsterdam, Amsterdam, The Netherlands.
在手术后的第三天,在微创食道切除术 (MIE) 后的恢复质量方面,椎间盘止痛疗法没有显示出优于外周止痛疗法的优势. 这两种方法都对MIE患者的疼痛管理和恢复有效.
科学领域:
- 麻醉学和疼痛管理
- 手术瘤学手术瘤学
- 关键护理医学 关键护理医学
背景情况:
- 准脊椎止痛疗法正在被探索,作为微创食道切除术 (MIE) 中外围止痛疗法的替代方案.
- 潜在的益处包括避免外围注射器相关的副作用,并增强术后恢复.
研究的目的:
- 在接受MIE的患者中,比较外围止痛和副脊椎止痛之间的康复质量.
- 评估二次结果,包括疼痛,生活质量和并发症.
主要方法:
- 一个随机控制的优越性试验,涉及192名接受MIE的食道癌症患者.
- 患者被分配给接受外周止痛或副脊椎止痛.
- 主要结局是术后第3天的康复质量 (QoR-40) 评分.
主要成果:
- 术后第3天的QoR-40得分在外周和副脊椎组之间没有显著差异.
- 外周止痛疗法在术后第一和第二天显示出更高的QoR-40得分,疼痛得分更低.
- 更多接受外周止痛治疗的患者在术后第一天需要血管压缩剂,而在准脊椎组中,尿导管在早期被移除.
结论:
- 在MIE后的术后第3天的康复质量方面,椎间盘止痛不优于外周止痛.
- 外周止痛和副脊椎止痛都是有效的技术来管理MIE患者的疼痛和恢复.
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