产前诊断和临床结果的孤立的巨型水箱Magna Magna
Oyoung Kim1, Subeen Hong2, Young Mi Jung3,4
1Department of Obstetrics and Gynecology, Yeouido St. Mary`s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Journal of child neurology
|October 3, 2024
概括
在胎儿中,孤立的巨型水通常会自发地消失,特别是在男性中,这些男性的发病率更高,测量更大. 大多数婴儿经历了有利的神经发育结果,尽管建议继续监测其他异常.
科学领域:
- 胎儿医学 胎儿医学
- 神经成像是一种神经成像.
- 儿科神经学 儿科神经学
背景情况:
- 孤立的超大水 (iMCM) 是一个产前发现,需要仔细评估.
- 了解iMCM的自然史和神经发育结果对于临床管理至关重要.
研究的目的:
- 为了研究被诊断为子宫内隔离的巨型水巨型 (iMCM) 的胎儿的临床结果.
- 分析神经发育结果,并确定与iMCM相关的因素.
主要方法:
- 多中心回顾性队列研究 (2010-2019) 涉及71名患有IMCM的胎儿.
- 排除其他中枢神经系统 (中枢神经系统) 或中枢神经系统外异常,染色体异常或感染的病例.
- 对母亲人口统计,产前,分娩和产后结果的分析.
主要成果:
- 在67.6%的病例中,iMCM在子宫内呈现自发回归.
- 产后持久性发生在18.3%,其中14.1%被诊断为其他中枢神经系统异常.
- 男性胎儿的发病率更高,水瓶大直径更大 (P=.045);发现了一例神经发育延迟的病例.
结论:
- 男性胎儿在IMCM病例中表现出更高的发病率和更大的cisterna magna尺寸.
- 良好的神经发育结果与iMCM有关,具有显著的子宫内分辨率.
- 持续的产前和产后监测至关重要,以检测相关的发育不良.
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