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改变的dNTP池加速了小鼠的瘤形成

Phong Tran1, Pradeep Mishra1, Leonard G Williams2,3

  • 1Department of Medical Biochemistry and Biophysics, Umeå University, Linnaeus väg 6, Umeå, SE 90736, Sweden.

Nucleic acids research
|October 3, 2024
PubMed
概括

通过核酸减少酶突变改变脱氧核酸三酸盐 (dNTP) 池可以加速小鼠的瘤发育. 这项研究将dNTP池的变化与癌症进展联系起来,并确定了不同的突变特征.

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