不完全切除率对于恶性虫和相关的危险因素
Maja Modin1, Helena Svensson1, Ylva Bergsten Wanders1
1Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Sahlgrenska University Hospital, Department of Dermatology and Venereology, Gothenburg, Sweden.
Acta dermato-venereologica
|October 3, 2024
概括
在16.7%的病例中,不完全的手术切除恶性虫 (LM) 发生. 风险因素包括头部和部位置,狭窄的边缘和手术前的活检,强调需要仔细的手术规划.
科学领域:
- 皮肤病学 皮肤病学
- 手术瘤学手术瘤学
- 病理学 病理学 病理学
背景情况:
- 常见的治疗 lentigo 恶性 (LM) 是外科切除.
- 关于不完整的LM切除的频率和风险因素的数据有限.
研究的目的:
- 为了确定初级LM中不完整的消毒率 (IER).
- 为了确定与不完整的LM切除相关的风险因素.
主要方法:
- 追溯分析了395个经过基因病理学确认的LMM (2014-2020年).
- 关于LM特征和IER的描述性统计.
- 单变量和多变量分析以确定风险因素.
主要成果:
- 整体IER为16.7%. 这是一个很好的结果.
- 不完全切除的危险因素包括头部和部病变 (p=0.0014),临床边缘<5毫米 (p=0.040),以及手术前活检 (p=0.023).
- 整形外科医生比皮肤科医生有更高的IER (p=0.036). 长度≥20毫米的LM有较高的IER (23.2%) 比小于10毫米 (12.9%) 的LM.
结论:
- 脊髓切除需要仔细规划,特别是在头部和部病变方面.
- 建议至少有5mm的临床边缘.
- 较大的病变 (≥20毫米),手术前活检和整形外科医生的参与可能表明手术复杂性增加.
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