围产和新生儿 Chikungunya 病毒传播:一个案例系列
Fátima C P A Di Maio Ferreira1, Ana M Bispo de Filippis2, Maria Elisabeth L Moreira3
1Follow-up Clinic, Neonatal Intensive Care Unit, Hospital Universtário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro, Department of Pediatrics and Neonatology (UNIRIO), Rio de Janeiro, Brazil.
Journal of the Pediatric Infectious Diseases Society
|October 3, 2024
概括
Chikungunya 病毒 (CHIKV) 可以从母亲传播给新生儿,导致严重的疾病. 在CHIKV流行病期间,在生命的第一周密切监测婴儿至关重要.
科学领域:
- 病毒学 病毒学
- 孕产妇和胎儿的医学
- 新生儿科学 新生儿科学
背景情况:
- 大规模的 chikungunya 病毒 (CHIKV) 流行带来风险,特别是在高出生率的国家.
- 增加的国际旅行增加了旅行者对树冠病毒的担忧.
- 垂直传播CHIKV可以导致严重的新生儿感染和潜在的神经损伤.
研究的目的:
- 审查CHIKV感染孕妇的临床和实验室发现.
- 描述CHIKV对新生儿的临床影响.
- 为了强调新生儿 chikungunya 的严重性.
主要方法:
- 进行了一系列雄心勃勃的案例.
- 已确认在子宫内或新生儿暴露于CHIKV的新生儿被纳入.
主要成果:
- 从病毒性母亲传播给新生儿的传播率约为62%.
- 新生儿 chikungunya 的关键症状包括发烧,易怒,皮疹和生命的第一个星期内的不良食.
- 这些迹象凸显了新生儿 chikungunya 的危急性质.
结论:
- 在受CHIKV影响的地区和旅行母亲的婴儿,在第一周密切监测新生儿是必不可少的.
- 本案例系列旨在提高新生儿科医生对母婴CHIKV传播的认识.
- 建议在生育年龄的妇女考虑接种CHIKV疫苗.
相关概念视频
Viral Meningitis
217
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
217
Arboviral Encephalitis
70
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
70
Cytomegalovirus Disease
108
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
108
Encephalitis l: Introduction
27
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
27


